Anion
Gap = Sodium + Potassium - CO2
+ Chloride
The
anion gap is used to measure the concentration of cations (sodium and potassium)
and the anions (chloride and CO2) in the extracellular fluid of the blood.
(Na
+ K) - (Cl + [HCO3-]) (all units mmol/L)
Aerobic
= The condition of requiring
oxygen; an aerobe is an organism which can live and grow only in the presence
of oxygen.
Bacteriostatic
=Inhibits or retards bacterial
growth.
Bactericide
=
Kills/destroys bacteria, but
not necessarily their spors.
Clostridium
= A genus of bacteria belonging
to the family Bacillaceae.These anaerobic, spore-forming rods are widely
distributed in nature, with more than 250 species recognized. They are
common in the soil and in the intestinal tract of humans and animals and
are frequently found in wound infections. In humans several species are
pathogenic, being the primary causative agents of gas gangrene.
Clostridium
tetani The causative organism of tetanus or lockjaw.It produces a powerful
exotoxin, one portion of which affects nerve tissue and the other of which
is hemolytic.
"Taber's
Cyclopedic Medical Dictionary," Copyright © 2001 by F. A. Davis Co.,
Phil., PA
Dermatophytes
= Fungi that can cause infections
of the skin, hair, and nails due to their ability to utilize keratin.
The
organisms colonize the keratin tissues and inflammation is caused by host
response to metabolic by-products. These infections are known as ringworm.
Endotoxins
= are part
of the cell wall of species classified as "gram-negative bacteria". The
toxic components of the gram-negative cell wall are called "lipopolysaccharides"
and are usually liberated as the result of cell death. All gram-negative
bacteria produce lipopolysaccharides, but only a few are also capable of
producing exotoxins.
Exotoxins
= are toxins that are secreted
by the cell either as part of the normal metabolic process or sometimes
as a result of cell death. Exotoxins are most often associated with contaminated
food & water or insect bites. Representative diseases = Botulism, cholera,
diphtheria, tetanus, bubonic plague, food poisoning, Whooping cough, gangrene,
Escherichia coli (enterotoxigenic strains), Staphylococcus aureus, Streptococcus
pyogenes.
FSH
= Follicle stimulating hormone
- A gonadotropic hormone of the anterior pituitary that stimulates growth
of follicles in the ovaries of females and function of the seminiferous
tubules in males.
Glucocorticoid(s)
= Any of a group of corticosteroids
(i.e. hydrocortisone or dexamethasone). Glucocorticoids are involved especially
in carbohydrate, protein, and fat metabolism, and increase liver glycogen
and blood sugar by increasing gluconeogenesis. They are anti-inflammatory
and immunosuppressive.
Hypothermia
=
Subnormal temperature of the
body.
Metabolite
=
1 : a product of metabolism
2
: a substance essential to the metabolism of a particular organism or to
a particular metabolic process
Motility
=1 : a product of metabolism
2
: a substance essential to the metabolism of a particular organism or to
a particular metabolic process
Osmotic
cathartic = osmotic
laxatives: attract and retain fluid in bowel
Prostacyclin
= a prostalandin that is
a metabolite of arachidonic acid, it inhibits platelet aggregation and
dilates blood vessels.
Prostaglandins
= Inflammation is caused by the
production of chemicals called prostaglandins. The prostaglandins increase
blood flow to injured tissues and increase the leaking of white blood cells
(WBCs) from capillaries (small blood vessels), which leads to the accumulation
of WBCs in the injured tissue. The WBCs (along with other cells) release
enzymes to clean up the damaged tissue, to help return it to normal. This
is all part of the normal healing process and it is necessary. However,
there is still the need to control inflammation, to prevent excessive pain
and scarring.
Retrovirus
= type of RNA virus that, unlike other RNA viruses, reproduces by transcribing
itself into DNA. An enzyme called reverse transcriptase allows a retrovirus’s
RNA to act as the template for this RNA-to-DNA transcription. The resultant
DNA inserts itself into a cell’s DNA and is reproduced along with the cell
and its daughters. The life cycle is completed when the viral DNA in selected
daughter cells makes an RNA copy of itself that covers itself in a protein
coat and leaves the cell. Retroviruses sometimes destroy the cells whose
DNA they alter, as with HIV, the virus that causes AIDS, and sometimes
cause them to become cancerous, as with the viruses that cause certain
leukemias. Lentiviruses are retroviruses that cause slowly progressing
diseases, such as AIDS.
Sensitivity
= the probability that a
truly diseased animal will test positive when the test is applied.
Specificity
=
the probability that a truly healthy (non-diseased) animal will test negative
when the test is applied.
Thromboxane
= any of several substances
that are formed from endoperoxides, causes constriction of vascular
and bronchial smooth muscle, and promote blood coagulation.