| |
|
|
Diet
|
Liver
|
Kidney
|
Serum
|
Spleen
|
| Deficient |
0.5-5.0
|
0.4-10.0
|
1.8-9.0
|
0.04-0.40
|
0.02-0.10
|
| Marginal |
5.0-10..0
|
15-25
|
|
0.40-0.80
|
1.0-2.0
|
| Adequate |
10-23
|
25.0-150
|
3.0-6.0
|
0.70-1.20
|
3.0
|
| High |
|
180-250
|
12-635
|
0.90-1.80
|
40-145
|
| Toxic |
|
230-2054
|
12-635
|
1.20-7.50
|
40-145
|
|
ppm
|
ppm
|
ppm
wet wt
|
|
ppm
wet wt
|
|
Diet
|
Fetal
Liver
|
Brain
|
Milk
|
Rib
|
Pancreas
|
Hair
|
| Deficient |
1.6-20.0
|
<2.0
|
0.006-0.100
|
|
|
<3.0
|
| Adequate |
30-114
|
3.0-4.0
|
0.1-0.9
|
6-13
|
6-11
|
5-8
|
| . |
ppm
wet wt
|
|
mg/L
|
|
ppm
dry wt
|
ppm
dry wt
|
Serum Cu is low in newborn for
several days.
Serum Cu is elevated during late pregnancy
and during pregnancy toxemia.
Kidney Cu may be elevated by infection,
trauma or toxicity
Enzootic
ataxia (swayback) in juvenile - padding hind legs followed by
posterior weakness, incoordination and flaccid paralysis progressing
to forelimbs resulting in prostration.
Poor growth rate or sudden death.
Cu
oxide needles administered orally in early pregnancy +2g to kids
at 5 weeks of age.
Goat
are 3 times more resisitant to toxicity than sheep.
Angora goats may be more susceptible to
toxicity than other breeds (unconfirmed).
Acute LD50 approximately 60mg.kg body weight.
10mg Cu as sulphate/kg body weight/day for
30-100 days is lethal.
Toxicity is enhanced by intramuscular Se
supplementation and apparently Monesin treatment.
25mf Cu/kg body wt/day for 19 weeks is toxic.
Hemolytic crisis - dullness,
depression, abomasal pain, tremors, hemoglobinuria, juandice,
brown muchus membrains, diarrhea, loss of appetite, arching of
back and grining of teeth.
High dietary selenium enhances
Cu deficiency.
Intramuscular selenium supplementation enhances
Cu storge in liver.
Serum Na and K increase Ca decreses during
toxicity hemolytic crisis.
| SOIL/PLANT
Cu INTERRELATIONSHIPS: |
Extractable
soil Cu needs to be >0.4mg.kg for cereal crops.
However plant Cu uptake can be affected
by plant species or cultivar, precipitation, and soil type and
is not highly correlated with soil Cu level.
Forages grown on saline soils contain lower
levels of Cu.
Legume feeds tend to have higher levels
of Cu than corn silage or grass hay.
Excessive precipitation reduces plant Cu
uptake.
Pasture treatment with 20 kg Cu sulphate/hectare
may help prevnet Cu deficienty.
Liming pasture high in Mo aggreavates Cu
deficiency.
Phosphate fertilizer high in S should be
avoided. |
Mineral
Levels in Animal Health
Diagnostic Data, Sherpa International
Clearbrook, BC Canada
R. Puls, 1994
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